In the clinical setting, the system serves over 100,000 patients throughout 11 health care facilities. These include nine tribal health centers, one employee health center and one tribal hospital. Additionally, CNHS offers a wide array of community, social, mental and public health programs such as the behavioral health, public health nursing, cancer prevention, diabetes prevention, Women Infants and Children, emergency medical services, environmental health, health research, emergency and risk management, clinical quality improvement and quality management. The Cherokee Nation Public Health programs work with a variety of tribal, public, private and community organizations to improve health outcomes.
CNHS operates two inpatient health facilities which include W.W. Hastings Hospital and the Jack Brown Center.
CNHS operates nine outpatient health facilities throughout the Cherokee Nation reservation.